REQUIREMENTS FOR THE PERFORMANCE OF THE ARRAY-CGH FOR CLINICAL GENETICS AND PRENATAL DIAGNOSIS
The array-CGH is done from the DNA of the sample, without the need for cell cultures.
The DNA may be extracted from a frozen cell pellet, blood, non-cultivated amniocytes, saliva impregnated in swabs, cytogenetic suspensions and/or paraffins.

The quality of the DNA will determine the quality of the array-CGH, and it is therefore essential to handle the sample correctly. The quantity needed is variable depending on the density of oligonucleotides of the array-CGH used.

IMPORTANT: All the samples must be accompanied by a Request Form, which must be appropriately filled out.

Samples must be kept at 4ºC until they are collected and they must be obtained under the following conditions:

 *Peripheral blood or blood from the umbilical cord:
   Heparin tube or EDTA (green, brown or purple top)
   Volume from 5 to 10 ml.

* Amniotic fluid:
   A sample of 4 to 5 ml in volume.

* Tumors or fresh tissue biopsies:
   Falcon type tube with 5 to 15 ml of PBS.